胆石病的临床防治与发病机制研究,腹腔镜手术器械及方法,胆石病基础研究
中国医师协会内镜医师分会微创保胆专委会副主任委员兼秘书长,中国非公立医疗机构协会胆石病专业委员会主任委员,上海市中西医结合学会外科专业委员会副主任委员,上海市浦东新区医学会微创外科专委会主任委员,世界华人内镜医师协会常务委员,世界内镜医师协会肝胆胃肠微创外科联盟副理事长。
1: Hu H, Shao W, Liu Q, Liu N, Wang Q, Xu J, Zhang X, Weng Z, Lu Q, Jiao L, Chen C, Sun H, Jiang Z, Zhang X, Gu A. Gut microbiota promotes cholesterol gallstone formation by modulating bile acid composition and biliary cholesterol secretion. Nat Commun. 2022 Jan 11;13(1):252. doi: 10.1038/s41467-021-27758-8. PMID: 35017486; PMCID: PMC8752841. 2: Wang B, Huang A, Jiang M, Li H, Bao W, Ding K, Jiang Z, Zhao G, Hu H. Risk Factors for Early Recurrence of Gallstones in Patients Undergoing Laparoscopy Combined With Choledochoscopic Lithotomy: A Single-Center Prospective Study. Front Surg. 2021 Nov 24;8:759390. doi: 10.3389/fsurg.2021.759390. PMID: 34901141; PMCID: PMC8651707. 3: Bao W, Xu A, Ni S, Wang B, Urmi H, Zhao B, You Y, Hu H. Is there a role for growth status in distinguishing gallbladder adenomas from cholesterol polyps? - A retrospective study based on 520 cholecystectomy patients. Scand J Gastroenterol. 2021 Dec;56(12):1450-1455. doi: 10.1080/00365521.2021.1970220. Epub 2021 Aug 30. PMID: 34461797. 4: Wang Q, Lu Q, Shao W, Jiang Z, Hu H. Dysbiosis of gut microbiota after cholecystectomy is associated with non-alcoholic fatty liver disease in mice. FEBS Open Bio. 2021 Jun 29;11(8):2329–39. doi: 10.1002/2211-5463.13243. Epub ahead of print. PMID: 34184432; PMCID: PMC8329777. 5: Hu H, Zhao G, Zhang K, Cai H, Jiang Z, Huang A, Cai J, Xu A, Li H, He C. The Clinical Application of a Self-developed Gasless Laparoendoscopic Operation Field Formation Device on Patients Undergoing Cholecystectomy. Surg Laparosc Endosc Percutan Tech. 2020 Oct;30(5):441-446. doi: 10.1097/SLE.0000000000000809. PMID: 32555068. 6: Chen Y, Weng Z, Liu Q, Shao W, Guo W, Chen C, Jiao L, Wang Q, Lu Q, Sun H, Gu A, Hu H, Jiang Z. FMO3 and its metabolite TMAO contribute to the formation of gallstones. Biochim Biophys Acta Mol Basis Dis. 2019 Oct 1;1865(10):2576-2585. doi: 10.1016/j.bbadis.2019.06.016. Epub 2019 Jun 26. PMID: 31251986. 7: Ye Z, Lu W, Liang L, Tang M, Wang Y, Li Z, Zeng H, Wang A, Lin M, Huang L, Wang H, Hu H. Mesenchymal stem cells overexpressing hepatocyte nuclear factor-4 alpha alleviate liver injury by modulating anti-inflammatory functions in mice. Stem Cell Res Ther. 2019 May 27;10(1):149. doi: 10.1186/s13287-019-1260-7. PMID: 31133062; PMCID: PMC6537220. 8: Shen W, Wang Y, Shao W, Wang Q, Jiang Z, Hu H. Dietary plant sterols prevented cholesterol gallstone formation in mice. Food Funct. 2021 Nov 29;12(23):11829-11837. doi: 10.1039/d1fo02695j. PMID: 34787152. 9: He C, Shen W, Chen C, Wang Q, Lu Q, Shao W, Jiang Z, Hu H. Circadian Rhythm Disruption Influenced Hepatic Lipid Metabolism, Gut Microbiota and Promoted Cholesterol Gallstone Formation in Mice. Front Endocrinol (Lausanne). 2021 Oct 21;12:723918. doi: 10.3389/fendo.2021.723918. PMID: 34745000; PMCID: PMC8567099. 10: Jiang M, Zhao G, Huang A, Zhang K, Wang B, Jiang Z, Ding K, Hu H. Comparison of a new gasless method and the conventional CO2 pneumoperitoneum method in laparoendoscopic single-site cholecystectomy: a prospective randomized clinical trial. Updates Surg. 2021 Dec;73(6):2231-2238. doi: 10.1007/s13304-021-01154-9. Epub 2021 Aug 31. PMID: 34463946; PMCID: PMC8606390.
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