肠-肝轴紊乱的病例机制、脓毒症肠损失的病理机制、纤维肌痛
中国实验动物学会神经科学技术专业委员会
常务委员兼秘书长
浦东新区医学会中西医结合康复专业委员会
副主委兼秘书长
上海市医学会疼痛学专科分会委员会 委员
中国女医师协会疼痛专业委员会委员会 委员
中国整形美容协会干细胞研究与应用分会委员会 青年委员
中国名族医药学会疼痛分会 理事
上海市中西医结合学会麻醉与疼痛专委会传统针法学组 秘书
上海市中西医结合学会麻醉与疼痛专委会疼痛康复学组 委员
上海市社会医疗机构协会疼痛医学分会肌筋膜疼痛功能训练专业委员 委员
医疗: 从事临床疼痛诊疗工作,每周三次专家门诊,收治住院患者年逾千例,年手术量800台,擅长全身弥漫性疼痛、纤维肌痛的诊治,擅长带状疱疹后遗神经痛、会阴痛、颈源性头痛、术后切口痛、肌筋膜疼痛综合症的诊治。 教学: 给同济大学麻醉学硕士生授课8学时;给灾难医学理论课8学时和实践课授课3学时。参编书籍:1)廖丽君. 疼痛学精要(肌筋膜疼痛的药物治疗,针灸疗法), 上海科学出版社, 翻译35千字, 副主译,2022. 2)廖丽君, 黄长顺, 血液保护学(合理用血与安全输血技术),浙江大学出版社,76千字,2008.06. 3)廖丽君,围术期血液保护(输血不良反应),浙江大学出版社,56千字,2007.03. 科研: 发表文章 1.Lijun Liao, Kai Markus Schneider, Mick Frissen, Till Strowig, Hanns-Ulrich Marschall, Huan Su, Daniela Kroy, Annika Wahlström, Eric J.C. Galvez, Antje Mohs, Jin Peng, Julia Jung, Johanna Reißing, Alexander Wree, Henning Wolfgang Zimmermann, Veerle Bieghs, Thomas Longerich, Christian Liedtke, Francisco Javier Cubero, Christian Trautwein. Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis. Gut. 2019 Aug;68(8):1477-1492. doi: 10.1136/gutjnl-2018-316670 (IF=23.059) 2. Francisco Javier Cubero*, Jin Peng*, Lijun Liao*, Huan Su, Gang Zhao, Miguel Eugenio Zoubek, Ricardo Macias-Rodriguez, Astrid Ruiz-Margain, Johanna Reißing, Henning W. Zimmermann, Nikolaus Gassler, Tom Luedde, Christian Liedtke, Maximilian Hatting, Christian Trautwein. Inactivation of caspase 8 in liver parenchymal cells confers protection against murine obstructive cholestasis. J Hepatol. 2018 Dec;69(6):1326-1334. (* Co-first author,IF=25.083) 3. Weizhi He, Kai Jiang, Hua Qiu, Lijun Liao#, Shasha Wang. 16-membered ring macrolides and erythromycin induce ermB expression by different mechanisms. BMC Microbiol 22, 152 (2022). https://doi.org/10.1186/s12866-022-02565-3(#Co-corresponding author,IF=3.060) 4. Junyi Duan, Xin Chen, Yixing Wang, Gang Zhao, Jing Li, Yi Gao, Jinyuan Zhang, Xiangrui Wang, Lijun Liao#, Yuelai Chen. Acupoint catgut embedding as adjunctive therapy for patients with gallstones. Journal of Clinical Gastroenterology. 2022 Jan 1; 56(1): e77-e83. doi:10.1097/MCG.0000000000001487. (#Co-corresponding author,IF=3.186) 5. Mick Frissen, Lijun Liao, Kai Schneider, Sonja Djudjaj, Philip Puchas, Johannes Haybaeck, Alexander Wree, Ulrike Rolle-Kampczyk, Martin von Bergen, Eicke Latz, Peter Boor and Christian Trautwein. Bidirectional role of NLRP3 during acute and chronic cholestatic liver injury. Hepatology. 2021 May;73(5):1836-1854. doi: 10.1002/hep.31494(IF=17.425) 6. Kai Markus Schneider, Carsten Elfers, Ahmed Ghallab, Carolin Victoria Schneider, Eric J C Galvez, Antje Mohs, Konrad Kilic, Lijun Liao, Anika Nier, Eicke Latz, Ina Bergheim, Christoph A Thaiss, Jan G Hengstler, Till Strowig, Christian Trautwein. Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury. Cell Mol Gastroenterol Hepatol. 2021;11(4):909-933. doi: 10.1016/j.jcmgh.2020.11.002. (IF=9.225) 7. Kai Markus Schneider, Lena Susanna Candels, Johannes R Hov, Maiju Myllys, Reham Hassan, Antje Mohs, Sebastian Zühlke, Lijun Liao, Carsten Elfers, Konrad Kilic, Marcus Henricsson, Antonio Molinaro, Maximilian Hatting, Ayham Zaza, Dirk Drasdo, Mick Frissen, Jan G Hengstler, Hanns-Ulrich Marschall, Ahmed Ghallab, Christian Trautwein. Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling. Nat Metab. 2021 Sep;3(9):1228-1241. doi: 10.1038/s42255-021-00452-1. (IF=7.745) 8. Kai Markus Schneider, Veerle Bieghs, Felix Heymann, Wei Hu, Daniela Dreymueller, Lijun Liao, Mick Frissen, Andreas Ludwig, Nikolaus Gassler, Oliver Pabst, Eicke Latz, Gernot Sellge, John Penders, Frank Tacke, Christian Trautwein. CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis. Hepatology. 2015, 62(5):1405–1416. doi: 10.1002/hep.27982.(IF=17.425) 科研项目 1.上海市浦江人才计划,2020PJD050,肠道MyD88促脓毒症肠-肝轴紊乱的病理机制研究。30万,2020.11-2022.10。在研,主持。 2. 国家自然科学基金 面上项目,81971814,回肠FXR-FGF19/15信号通路在脓毒症胆汁淤积性肝损伤中的调控机制研究,55万,2020.01-2023.12。在研,主持。 3. 上海市浦东新区卫生系统学科带头人培养计划,PWRd2020-06,脓毒症肠-肝轴紊乱的病理机制研究。20万,2020.10-2024.09。在研,主持。
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